What Does POCT Stand For?
POCT stands for Point-of-Care Testing, which refers to clinical laboratory testing performed at or near the site of patient care, outside the central laboratory. 1
Definition and Core Concept
Point-of-care testing is laboratory diagnostics performed near or at the location where clinical care is delivered, combining sample collection, analysis, and reporting of results into an integrated testing structure with a simple user interface. 2 The testing is typically performed by clinical staff such as physicians or nurses who are not laboratory-trained personnel, rather than by laboratory professionals. 3, 4
Key Characteristics
Location: POCT can be performed in diverse settings including:
Turnaround Time: The primary advantage is rapid result availability, as POCT circumvents specimen transportation and processing steps required by central laboratories, allowing for immediate clinical decision-making. 3, 5
Sample Requirements: POCT devices typically require small specimen volumes, making them particularly valuable in pediatric populations. 5
Clinical Applications Referenced in Guidelines
The KDIGO guidelines specifically recommend POCT for creatinine and urine albumin measurement where laboratory access is limited or when testing at the point-of-care facilitates the clinical pathway. 1 The same quality standards that apply to central laboratory testing must be maintained for POCT devices, including external quality assessment and proper specimen collection procedures. 1
Quality Assurance Requirements
- POCT programs require rigorous oversight including quality control, external quality assurance procedures, staff training, and connectivity to laboratory information systems for accreditation under ISO 22870. 3
- Device selection, initial and ongoing verification, reagent and quality control lot changes, and operator management are essential components of POCT quality assurance. 4
- Despite being performed outside the laboratory, POCT must adhere to the same pre-analytical, analytical, and post-analytical quality criteria as central laboratory testing. 1